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Crones Disease: What Do Your Medicines Do?

By: PerfectDarknessTint


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If you are taking medicines for your Crones disease, you will probably recognize a lot of the symptoms and side effects mentioned in this article. After a summary of the most problematic sides of mainstream medication, a possible solution is given to improve life quality and health in the long run on a solid basis.

Medicines are the most common Crones disease treatment. While none can cure this inflammatory bowel disease (IBD), they are used to try to reduce the swelling that causes the symptoms. The most frequently used medicines for Crones disease are Aminosalicylates and Corticosteroids to Block Inflammation, Antibiotics to Control Intestinal Bacteria, Immunomodulators to Calm the Immune System, and Biologic Therapies for Moderate or Severe Crones disease. Brand names of these medicines are (amongst others): - Aminosalicylates : Mesalamine (Asacol, Pentasa), Balsalazide (Dipentum), Olsalazine (Colazal) - Corticosteroids: Prednisone (Deltasone), Budesonide (Entocort EC) , Hydrocortisone, Methylprednisolone (Medrol) - Antibiotics: Ciprofloxacin (Cipro), Metronidazole (Flagyl) Immunomodulators: Azathioprine (Imuran, Azasan),6-mercaptopurine (Purinethol, 6-MP), Methotrexate (MTX, Rheumatrex, Mexate) , Tacrolimus (Prograf), Cyclosporine A (Sandimmune, Neoral) - Biologic Therapies: Infliximab (Remicade), Adalimumab (Humira).

If we have a closer look at the side effects of these medicaments, we will discover some very unattractive pictures.. Don't forget that the longer we take a medicine, the more likely the side effects are to develop. In our case, we suffer from a chronic disease, and if we do not find another solution, we will be stuck taking medicines for the rest of our lives. Known side effects of the mentioned medicines are: Diarrhea Headache, dizziness Increased risk of bleeding in the gastrointestinal tract Indigestion, nausea, gas Hair loss Rash Decrease in white blood cells High blood pressure Mood swings, psychosis, insomnia Weight gain, moon facies Acne, increased facial hair, stretch marks Increased risk of infection Osteoporosis Vomiting Cough Sinus infections Sore throat

Some of the therapies have other drawbacks as well. Biologic therapies need frequent injections, and other medicines have a better effect when taken as an enema or a suppository. Not very pleasant if done frequently.

I want to make a special note on corticosteroids. Some corticosteroids can also be given intravenously. Corticosteroids can have severe side effects, like an increased risk of infection, so even the mainstream doctors will hesitate to prescribe them for a longer period of time. If you want to stop taking corticosteroids, make sure you taper off them gradually. Stopping them suddenly can worsen side effects.

Antibiotics are known to be bad for you intestines. Even my vet prescribes probiotics to my dog if she has to take antibiotics to maintain the level of good bacteria in the gut as high as possible. If you take antibiotics over a longer period of time, or you take antibiotics with regular intervals, your natural bacteria level in your gut will be very low; good bacteria and bad bacteria. If you have a low level of good bacteria, your gut is missing it's natural shield against attacks of bad bacteria, and the question is if this actually is not worsening the overall situation.

Injectable or oral immunomodulators are used if the patient did not react well on other medicines to reduce the swelling, or for patients which developed complications like fistulas. Often they are given in combination with corticosteroids, whereby you can take lower doses of the latter, because their effect is increased by the immunomodulators. Immunomodulators are more expensive than other medicines used for Crones Disease, and you are at higher risk to develop secondary infections or other illnesses because they suppress the immune system. Doctors advise you to have your blood monitored regularly to see the effect on your bone marrow, liver and kidneys.

The newest and most expensive treatment for Crones Disease is Biological therapy. It can be used to improve the symptoms, but will have to be taken on the long run to avoid backfalls. At the moment it is only used for patients which do not respond to other treatments, as the side effects can be severe. It suppresses the immune system and hence makes us prone to infections. There is even evidence that it increases the risk of conditions like blood infections, tuberculosis, and lymphoma.

Some medicines will interacts with other common drugs like birth control pills, and they can even break down vitamins or stop there absorption into the bloodstream. When you have diarrhea you will have to take medicines for that, and you will have to compensate the fluid loss.

It is clear that an alternative way to boost our immune system and stimulate the growth of beneficial bacteria in our gut would be more than welcome. Initially as an extra way to improve our health, and if possible later as a substitute for the mentioned treatments.

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Crones Disease is a chronic disease which lays a heavy burden on the patient and his family. Side effects of medicines can make life even worse; here you will find a proven approach to help your body overcome your Crones Disease.



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